Kofi Dadzie Kwofie, Emmanuel Pacia Hernandez, Anisuzzaman, Hayato Kawada, Yuki Koike, Sana Sasaki, Takahiro Inoue, Kei Jimbo, Fusako Mikami, Danielle Ladzekpo, Rika Umemiya-Shirafuji, Kayoko Yamaji, Tetsuya Tanaka, Makoto Matsubayashi, Md Abdul Alim, Samuel Kweku Dadzie, Shiroh Iwanaga, Naotoshi Tsuji & Takeshi Hatta
‘RNA activation in ticks’
volume 13, Article number: 9341 Scientific Reports 2023

RNA活性化(RNA activation, RNAa)は、遺伝子制御の一つのメカニズムであり、転写活性化やmRNAの安定化に関与します。このメカニズムは、転写後の遺伝子発現を抑制するRNA干渉(RNA intereference, RNAi)とは対照的なものとして、2006年に報告されました。私たちは、マダニの有用な物質を探索する過程で、初めてマダニにおいてRNAa現象が存在することを突き止めました。

DOI : https://doi.org/10.1038/s41598-023-36523-4

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