Hajime Koizumi, Wataru Fujii, Chizu Sanjoba, Yasuyuki Goto
‘BAFF induces CXCR5 expression during B cell differentiation in bone marrow’
B B Reports, Volume 34, July 2023, 101451

細胞の分化において重要な役割を果たすサイトカインであるBAFFですが、B細胞の発生初期、つまり骨髄におけるB細胞発育への影響については議論が残ります。今回、骨髄での未成熟B細胞の発生において、BAFFがケモカイン受容体CXCR5の発現に重要であることを明らかにしました。

DOI : https://doi.org/10.1016/j.bbrep.2023.101451

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