Naoyoshi Nagata, Tadashi Takeuchi, Hiroaki Masuoka, Ryo Aoki, Masahiro Ishikane, Noriko Iwamoto, Masaya Sugiyama, Wataru Suda, Yumiko Nakanishi, Junko Terada-Hirashima, Moto Kimura, Tomohiko Nishijima, Hiroshi Inooka, Tohru Miyoshi-Akiyama, Yasushi Kojima, Chikako Shimokawa, Hajime Hisaeda, Fen Zhang, Hiroshi Ohno
‘Human Gut Microbiota and Its Metabolites Impact Immune Responses in COVID-19 and Its Complications’
Gastroenterology Available online 23 September 2022

COVID-19患者やその合併症を有する患者ではユニークな腸内環境の変化がみられ、過剰な免疫応答と関わっていることを発見しました。同じ日本人でも新型コロナウイルスの感受性やCOVID-19に伴う合併症リスクの違いがあるのは、腸内環境の個人差が寄与しているかもしれません。腸内環境の個人差はワクチンの効果や副反応の個人差にも影響する可能性があり今後の研究が期待されます。

DOI : https://doi.org/10.1053/j.gastro.2022.09.024

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