Naoyoshi Nagata, Tadashi Takeuchi, Hiroaki Masuoka, Ryo Aoki, Masahiro Ishikane, Noriko Iwamoto, Masaya Sugiyama, Wataru Suda, Yumiko Nakanishi, Junko Terada-Hirashima, Moto Kimura, Tomohiko Nishijima, Hiroshi Inooka, Tohru Miyoshi-Akiyama, Yasushi Kojima, Chikako Shimokawa, Hajime Hisaeda, Fen Zhang, Hiroshi Ohno
‘Human Gut Microbiota and Its Metabolites Impact Immune Responses in COVID-19 and Its Complications’
Gastroenterology Available online 23 September 2022

We discovered that COVID-19 patients and patients with complications show unique changes in the intestinal environment, which are associated with excessive immune responses. Individual differences in the intestinal environment may contribute to the differences in susceptibility to COVID-19 and the risk of complications associated with COVID-19 among Japanese people. Individual differences in the intestinal environment may affect individual differences in vaccine efficacy and adverse reactions, and future research is expected.

DOI : https://doi.org/10.1053/j.gastro.2022.09.024

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